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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric CRWrnafold TurboFold(seed)
MCC 0.513 > 0.496
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387 > 0.507 ± 0.354
Sensitivity 0.524 > 0.476
Positive Predictive Value 0.516 < 0.531
Total TP 66 > 60
Total TN 8854 < 8869
Total FP 83 > 66
Total FP CONTRA 21 > 17
Total FP INCONS 41 > 36
Total FP COMP 21 > 13
Total FN 60 < 66
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8854
Total FP 83
Total FP CONTRA 21
Total FP INCONS 41
Total FP COMP 21
Total FN 60
Total Scores
MCC 0.513
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387
Sensitivity 0.524
Positive Predictive Value 0.516
Nr of predictions 6

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 60
Total TN 8869
Total FP 66
Total FP CONTRA 17
Total FP INCONS 36
Total FP COMP 13
Total FN 66
Total Scores
MCC 0.496
Average MCC ± 95% Confidence Intervals 0.507 ± 0.354
Sensitivity 0.476
Positive Predictive Value 0.531
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.