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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) RNASLOpt
MCC 0.698 > 0.459
Average MCC ± 95% Confidence Intervals 0.668 ± 0.379 > 0.549 ± 0.451
Sensitivity 0.557 > 0.456
Positive Predictive Value 0.880 > 0.474
Total TP 44 > 36
Total TN 6871 > 6845
Total FP 10 < 49
Total FP CONTRA 3 < 17
Total FP INCONS 3 < 23
Total FP COMP 4 < 9
Total FN 35 < 43
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and RNASLOpt).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 44
Total TN 6871
Total FP 10
Total FP CONTRA 3
Total FP INCONS 3
Total FP COMP 4
Total FN 35
Total Scores
MCC 0.698
Average MCC ± 95% Confidence Intervals 0.668 ± 0.379
Sensitivity 0.557
Positive Predictive Value 0.880
Nr of predictions 4

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.33 0.25 0.45 5 4505 8 3 3 2 15
4AOB_A 0.89 0.79 1.00 23 1414 2 0 0 2 6
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 36
Total TN 6845
Total FP 49
Total FP CONTRA 17
Total FP INCONS 23
Total FP COMP 9
Total FN 43
Total Scores
MCC 0.459
Average MCC ± 95% Confidence Intervals 0.549 ± 0.451
Sensitivity 0.456
Positive Predictive Value 0.474
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.