CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidHomfold‑LAST & Murlet(20) [.zip] - may take several seconds...


Overview

Metric CentroidHomfold‑LAST Murlet(20)
MCC 0.726 > 0.654
Average MCC ± 95% Confidence Intervals 0.737 ± 0.258 > 0.635 ± 0.263
Sensitivity 0.644 > 0.576
Positive Predictive Value 0.825 > 0.752
Total TP 85 > 76
Total TN 9217 < 9219
Total FP 32 = 32
Total FP CONTRA 9 = 9
Total FP INCONS 9 < 16
Total FP COMP 14 > 7
Total FN 47 < 56
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CentroidHomfold-LAST and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidHomfold‑LAST and Murlet(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidHomfold-LAST and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidHomfold‑LAST and Murlet(20)).

^top





Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 85
Total TN 9217
Total FP 32
Total FP CONTRA 9
Total FP INCONS 9
Total FP COMP 14
Total FN 47
Total Scores
MCC 0.726
Average MCC ± 95% Confidence Intervals 0.737 ± 0.258
Sensitivity 0.644
Positive Predictive Value 0.825
Nr of predictions 6

^top



2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.77 0.66 0.90 19 1512 2 1 1 0 10
4A1C_2 0.24 0.25 0.24 5 4495 29 8 8 13 15
4AOB_A 0.85 0.72 1.00 21 1416 1 0 0 1 8
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

^top



Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 76
Total TN 9219
Total FP 32
Total FP CONTRA 9
Total FP INCONS 16
Total FP COMP 7
Total FN 56
Total Scores
MCC 0.654
Average MCC ± 95% Confidence Intervals 0.635 ± 0.263
Sensitivity 0.576
Positive Predictive Value 0.752
Nr of predictions 6

^top



2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.81 0.67 1.00 16 850 0 0 0 0 8
3SD1_A 0.82 0.83 0.83 24 1504 5 4 1 0 5
4A1C_2 0.22 0.25 0.20 5 4491 24 5 15 4 15
4AOB_A 0.87 0.76 1.00 22 1415 3 0 0 3 7
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.