CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Carnac(seed)
MCC 0.570 > 0.202
Average MCC ± 95% Confidence Intervals 0.592 ± 0.249 > 0.093 ± 0.258
Sensitivity 0.515 > 0.041
Positive Predictive Value 0.641 < 1.000
Total TP 50 > 4
Total TN 7371 < 7445
Total FP 42 > 0
Total FP CONTRA 6 > 0
Total FP INCONS 22 > 0
Total FP COMP 14 > 0
Total FN 47 < 93
P-value 0.0

^top




Performance plots


  1. Comparison of performance of ContextFold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

^top





Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 50
Total TN 7371
Total FP 42
Total FP CONTRA 6
Total FP INCONS 22
Total FP COMP 14
Total FN 47
Total Scores
MCC 0.570
Average MCC ± 95% Confidence Intervals 0.592 ± 0.249
Sensitivity 0.515
Positive Predictive Value 0.641
Nr of predictions 5

^top



2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top



Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 7445
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 93
Total Scores
MCC 0.202
Average MCC ± 95% Confidence Intervals 0.093 ± 0.258
Sensitivity 0.041
Positive Predictive Value 1.000
Nr of predictions 5

^top



2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.