CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold RNASampler(seed)
MCC 0.413 > 0.232
Average MCC ± 95% Confidence Intervals 0.418 ± 2.004 > 0.186 ± 2.685
Sensitivity 0.395 > 0.211
Positive Predictive Value 0.441 > 0.267
Total TP 15 > 8
Total TN 5010 < 5014
Total FP 32 > 30
Total FP CONTRA 3 < 4
Total FP INCONS 16 < 18
Total FP COMP 13 > 8
Total FN 23 < 30
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 15
Total TN 5010
Total FP 32
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 13
Total FN 23
Total Scores
MCC 0.413
Average MCC ± 95% Confidence Intervals 0.418 ± 2.004
Sensitivity 0.395
Positive Predictive Value 0.441
Nr of predictions 2

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 8
Total TN 5014
Total FP 30
Total FP CONTRA 4
Total FP INCONS 18
Total FP COMP 8
Total FN 30
Total Scores
MCC 0.232
Average MCC ± 95% Confidence Intervals 0.186 ± 2.685
Sensitivity 0.211
Positive Predictive Value 0.267
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.