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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold TurboFold(seed)
MCC 0.570 > 0.431
Average MCC ± 95% Confidence Intervals 0.592 ± 0.249 > 0.467 ± 0.448
Sensitivity 0.515 > 0.412
Positive Predictive Value 0.641 > 0.465
Total TP 50 > 40
Total TN 7371 > 7363
Total FP 42 < 59
Total FP CONTRA 6 < 15
Total FP INCONS 22 < 31
Total FP COMP 14 > 13
Total FN 47 < 57
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 50
Total TN 7371
Total FP 42
Total FP CONTRA 6
Total FP INCONS 22
Total FP COMP 14
Total FN 47
Total Scores
MCC 0.570
Average MCC ± 95% Confidence Intervals 0.592 ± 0.249
Sensitivity 0.515
Positive Predictive Value 0.641
Nr of predictions 5

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 40
Total TN 7363
Total FP 59
Total FP CONTRA 15
Total FP INCONS 31
Total FP COMP 13
Total FN 57
Total Scores
MCC 0.431
Average MCC ± 95% Confidence Intervals 0.467 ± 0.448
Sensitivity 0.412
Positive Predictive Value 0.465
Nr of predictions 5

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.