CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Contrafold Mastr(seed)
MCC 0.623 > 0.000
Average MCC ± 95% Confidence Intervals 0.654 ± 0.142 > 0.000 ± 0.000
Sensitivity 0.647 > 0.000
Positive Predictive Value 0.606 > 0.000
Total TP 372 > 0
Total TN 77101 < 77715
Total FP 290 > 0
Total FP CONTRA 107 > 0
Total FP INCONS 135 > 0
Total FP COMP 48 > 0
Total FN 203 < 575
P-value 3.57327336088e-08

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Performance plots


  1. Comparison of performance of Contrafold and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Contrafold and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 372
Total TN 77101
Total FP 290
Total FP CONTRA 107
Total FP INCONS 135
Total FP COMP 48
Total FN 203
Total Scores
MCC 0.623
Average MCC ± 95% Confidence Intervals 0.654 ± 0.142
Sensitivity 0.647
Positive Predictive Value 0.606
Nr of predictions 19

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.46 0.39 0.58 7 516 5 3 2 0 11
2ZZN_D 0.93 0.95 0.91 21 961 3 2 0 1 1
3A2K_C 0.49 0.55 0.46 12 1082 14 3 11 0 10
3A3A_A 0.97 0.93 1.00 28 1472 0 0 0 0 2
3GX2_A 0.93 0.89 0.96 25 1423 2 1 0 1 3
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3IYQ_A 0.28 0.39 0.20 20 22341 95 44 35 16 31
3IZ4_A 0.57 0.58 0.57 55 25440 49 18 23 8 40
3JYV_7 -0.02 0.00 0.00 0 1091 20 4 16 0 20
3LA5_A 0.91 0.84 1.00 21 933 0 0 0 0 4
3NPB_A 0.86 0.84 0.89 31 2243 9 1 3 5 6
3O58_3 0.32 0.36 0.29 8 4736 21 7 13 1 14
3PDR_A 0.83 0.86 0.80 43 4786 13 5 6 2 7
3RKF_A 0.87 0.83 0.91 20 844 2 2 0 0 4
3SD1_A 0.68 0.69 0.69 20 1504 9 5 4 0 9
4A1C_2 0.21 0.25 0.19 5 4489 33 9 13 11 15
4AOB_A 0.53 0.52 0.56 15 1410 13 3 9 1 14
4ENB_A 0.85 0.73 1.00 11 461 1 0 0 1 4
4ENC_A 0.85 0.73 1.00 11 485 1 0 0 1 4

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 77715
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 575
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 19

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 528 0 0 0 0 18
2ZZN_D 0.00 0.00 0.00 0 984 0 0 0 0 22
3A2K_C 0.00 0.00 0.00 0 1108 0 0 0 0 22
3A3A_A 0.00 0.00 0.00 0 1500 0 0 0 0 30
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3IYQ_A 0.00 0.00 0.00 0 22440 0 0 0 0 51
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3JYV_7 0.00 0.00 0.00 0 1111 0 0 0 0 20
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.