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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold PPfold(seed)
MCC 0.740 > 0.182
Average MCC ± 95% Confidence Intervals 0.773 ± 0.239 > 0.082 ± 0.210
Sensitivity 0.708 > 0.046
Positive Predictive Value 0.786 > 0.750
Total TP 92 > 6
Total TN 5215 < 5324
Total FP 26 > 2
Total FP CONTRA 7 > 0
Total FP INCONS 18 > 2
Total FP COMP 1 > 0
Total FN 38 < 124
P-value 0.0

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Performance plots


  1. Comparison of performance of Cylofold and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and PPfold(seed)).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 92
Total TN 5215
Total FP 26
Total FP CONTRA 7
Total FP INCONS 18
Total FP COMP 1
Total FN 38
Total Scores
MCC 0.740
Average MCC ± 95% Confidence Intervals 0.773 ± 0.239
Sensitivity 0.708
Positive Predictive Value 0.786
Nr of predictions 6

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 6
Total TN 5324
Total FP 2
Total FP CONTRA 0
Total FP INCONS 2
Total FP COMP 0
Total FN 124
Total Scores
MCC 0.182
Average MCC ± 95% Confidence Intervals 0.082 ± 0.210
Sensitivity 0.046
Positive Predictive Value 0.750
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.49 0.33 0.75 6 520 2 0 2 0 12
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.