CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold RNASampler(seed)
MCC 0.659 > 0.596
Average MCC ± 95% Confidence Intervals 0.669 ± 0.324 > 0.535 ± 0.642
Sensitivity 0.667 > 0.505
Positive Predictive Value 0.660 < 0.712
Total TP 62 > 47
Total TN 7597 < 7625
Total FP 42 > 24
Total FP CONTRA 12 > 5
Total FP INCONS 20 > 14
Total FP COMP 10 > 5
Total FN 31 < 46
P-value 0.0

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Performance plots


  1. Comparison of performance of Cylofold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 62
Total TN 7597
Total FP 42
Total FP CONTRA 12
Total FP INCONS 20
Total FP COMP 10
Total FN 31
Total Scores
MCC 0.659
Average MCC ± 95% Confidence Intervals 0.669 ± 0.324
Sensitivity 0.667
Positive Predictive Value 0.660
Nr of predictions 4

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
3O58_3 0.42 0.50 0.35 11 4733 30 9 11 10 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 47
Total TN 7625
Total FP 24
Total FP CONTRA 5
Total FP INCONS 14
Total FP COMP 5
Total FN 46
Total Scores
MCC 0.596
Average MCC ± 95% Confidence Intervals 0.535 ± 0.642
Sensitivity 0.505
Positive Predictive Value 0.712
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.