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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Multilign(20)
MCC 0.606 > 0.581
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272 < 0.583 ± 0.267
Sensitivity 0.561 < 0.576
Positive Predictive Value 0.667 > 0.598
Total TP 74 < 76
Total TN 9209 > 9193
Total FP 59 < 60
Total FP CONTRA 16 < 17
Total FP INCONS 21 < 34
Total FP COMP 22 > 9
Total FN 58 > 56
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Multilign(20)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 74
Total TN 9209
Total FP 59
Total FP CONTRA 16
Total FP INCONS 21
Total FP COMP 22
Total FN 58
Total Scores
MCC 0.606
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272
Sensitivity 0.561
Positive Predictive Value 0.667
Nr of predictions 6

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 76
Total TN 9193
Total FP 60
Total FP CONTRA 17
Total FP INCONS 34
Total FP COMP 9
Total FN 56
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.583 ± 0.267
Sensitivity 0.576
Positive Predictive Value 0.598
Nr of predictions 6

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15
4AOB_A 0.59 0.55 0.64 16 1412 10 3 6 1 13
4ENB_A 0.39 0.33 0.50 5 462 6 0 5 1 10
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.