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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) PPfold(seed)
MCC 0.606 > 0.036
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272 > 0.016 ± 0.042
Sensitivity 0.561 > 0.008
Positive Predictive Value 0.667 > 0.200
Total TP 74 > 1
Total TN 9209 < 9315
Total FP 59 > 23
Total FP CONTRA 16 > 0
Total FP INCONS 21 > 4
Total FP COMP 22 > 19
Total FN 58 < 131
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and PPfold(seed)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 74
Total TN 9209
Total FP 59
Total FP CONTRA 16
Total FP INCONS 21
Total FP COMP 22
Total FN 58
Total Scores
MCC 0.606
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272
Sensitivity 0.561
Positive Predictive Value 0.667
Nr of predictions 6

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 1
Total TN 9315
Total FP 23
Total FP CONTRA 0
Total FP INCONS 4
Total FP COMP 19
Total FN 131
Total Scores
MCC 0.036
Average MCC ± 95% Confidence Intervals 0.016 ± 0.042
Sensitivity 0.008
Positive Predictive Value 0.200
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.10 0.05 0.20 1 4511 23 0 4 19 19
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.