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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric MXScarna(20) RNASLOpt
MCC 0.477 > 0.459
Average MCC ± 95% Confidence Intervals 0.469 ± 0.391 < 0.549 ± 0.451
Sensitivity 0.430 < 0.456
Positive Predictive Value 0.540 > 0.474
Total TP 34 < 36
Total TN 6858 > 6845
Total FP 50 > 49
Total FP CONTRA 10 < 17
Total FP INCONS 19 < 23
Total FP COMP 21 > 9
Total FN 45 > 43
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 34
Total TN 6858
Total FP 50
Total FP CONTRA 10
Total FP INCONS 19
Total FP COMP 21
Total FN 45
Total Scores
MCC 0.477
Average MCC ± 95% Confidence Intervals 0.469 ± 0.391
Sensitivity 0.430
Positive Predictive Value 0.540
Nr of predictions 4

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 36
Total TN 6845
Total FP 49
Total FP CONTRA 17
Total FP INCONS 23
Total FP COMP 9
Total FN 43
Total Scores
MCC 0.459
Average MCC ± 95% Confidence Intervals 0.549 ± 0.451
Sensitivity 0.456
Positive Predictive Value 0.474
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.