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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric MXScarna(20) RNAwolf
MCC 0.606 > 0.442
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272 > 0.439 ± 0.284
Sensitivity 0.561 > 0.439
Positive Predictive Value 0.667 > 0.460
Total TP 74 > 58
Total TN 9209 > 9194
Total FP 59 < 82
Total FP CONTRA 16 < 17
Total FP INCONS 21 < 51
Total FP COMP 22 > 14
Total FN 58 < 74
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and RNAwolf).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 74
Total TN 9209
Total FP 59
Total FP CONTRA 16
Total FP INCONS 21
Total FP COMP 22
Total FN 58
Total Scores
MCC 0.606
Average MCC ± 95% Confidence Intervals 0.580 ± 0.272
Sensitivity 0.561
Positive Predictive Value 0.667
Nr of predictions 6

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 58
Total TN 9194
Total FP 82
Total FP CONTRA 17
Total FP INCONS 51
Total FP COMP 14
Total FN 74
Total Scores
MCC 0.442
Average MCC ± 95% Confidence Intervals 0.439 ± 0.284
Sensitivity 0.439
Positive Predictive Value 0.460
Nr of predictions 6

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.89 0.83 0.95 20 845 1 0 1 0 4
3SD1_A 0.58 0.59 0.59 17 1504 12 2 10 0 12
4A1C_2 0.12 0.15 0.10 3 4487 38 12 14 12 17
4AOB_A 0.26 0.24 0.30 7 1414 17 2 14 1 22
4ENB_A 0.45 0.40 0.55 6 461 5 1 4 0 9
4ENC_A 0.34 0.33 0.38 5 483 9 0 8 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.