CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) Multilign(seed)
MCC 0.643 > 0.629
Average MCC ± 95% Confidence Intervals 0.572 ± 0.642 > 0.569 ± 0.654
Sensitivity 0.600 > 0.580
Positive Predictive Value 0.706 > 0.699
Total TP 60 > 58
Total TN 4279 < 4281
Total FP 31 > 26
Total FP CONTRA 6 < 7
Total FP INCONS 19 > 18
Total FP COMP 6 > 1
Total FN 40 < 42
P-value 0.0

^top




Performance plots


  1. Comparison of performance of MXScarna(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

^top





Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 60
Total TN 4279
Total FP 31
Total FP CONTRA 6
Total FP INCONS 19
Total FP COMP 6
Total FN 40
Total Scores
MCC 0.643
Average MCC ± 95% Confidence Intervals 0.572 ± 0.642
Sensitivity 0.600
Positive Predictive Value 0.706
Nr of predictions 4

^top



2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 12 0 10 2 18
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 4 4 1 7
4AOB_A 0.71 0.69 0.74 20 1410 10 2 5 3 9

^top



Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 4281
Total FP 26
Total FP CONTRA 7
Total FP INCONS 18
Total FP COMP 1
Total FN 42
Total Scores
MCC 0.629
Average MCC ± 95% Confidence Intervals 0.569 ± 0.654
Sensitivity 0.580
Positive Predictive Value 0.699
Nr of predictions 4

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.