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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) NanoFolder
MCC 0.468 > 0.336
Average MCC ± 95% Confidence Intervals 0.402 ± 0.490 > 0.394 ± 0.460
Sensitivity 0.415 = 0.415
Positive Predictive Value 0.540 > 0.288
Total TP 34 = 34
Total TN 6914 > 6859
Total FP 46 < 101
Total FP CONTRA 7 < 25
Total FP INCONS 22 < 59
Total FP COMP 17 = 17
Total FN 48 = 48
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and NanoFolder).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 34
Total TN 6914
Total FP 46
Total FP CONTRA 7
Total FP INCONS 22
Total FP COMP 17
Total FN 48
Total Scores
MCC 0.468
Average MCC ± 95% Confidence Intervals 0.402 ± 0.490
Sensitivity 0.415
Positive Predictive Value 0.540
Nr of predictions 4

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 12 0 10 2 18
4A1C_2 0.45 0.40 0.50 8 4500 20 4 4 12 12
4AOB_A 0.71 0.69 0.74 20 1410 10 2 5 3 9
4ENC_A 0.48 0.40 0.60 6 486 4 1 3 0 9

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 34
Total TN 6859
Total FP 101
Total FP CONTRA 25
Total FP INCONS 59
Total FP COMP 17
Total FN 48
Total Scores
MCC 0.336
Average MCC ± 95% Confidence Intervals 0.394 ± 0.460
Sensitivity 0.415
Positive Predictive Value 0.288
Nr of predictions 4

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.