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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) RNASLOpt
MCC 0.476 > 0.461
Average MCC ± 95% Confidence Intervals 0.429 ± 0.340 < 0.536 ± 0.307
Sensitivity 0.412 < 0.443
Positive Predictive Value 0.563 > 0.494
Total TP 40 < 43
Total TN 7378 > 7362
Total FP 48 < 53
Total FP CONTRA 7 < 17
Total FP INCONS 24 < 27
Total FP COMP 17 > 9
Total FN 57 > 54
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and RNASLOpt).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 40
Total TN 7378
Total FP 48
Total FP CONTRA 7
Total FP INCONS 24
Total FP COMP 17
Total FN 57
Total Scores
MCC 0.476
Average MCC ± 95% Confidence Intervals 0.429 ± 0.340
Sensitivity 0.412
Positive Predictive Value 0.563
Nr of predictions 5

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 12 0 10 2 18
4A1C_2 0.45 0.40 0.50 8 4500 20 4 4 12 12
4AOB_A 0.71 0.69 0.74 20 1410 10 2 5 3 9
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 1 3 0 9

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 7362
Total FP 53
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 9
Total FN 54
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307
Sensitivity 0.443
Positive Predictive Value 0.494
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.