CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	MXScarna(seed)		RNAwolf
MCC	0.593	>	0.451
Average MCC ± 95% Confidence Intervals	0.535 ± 0.268	>	0.450 ± 0.230
Sensitivity	0.533	>	0.447
Positive Predictive Value	0.672	>	0.472
Total TP	80	>	67
Total TN	9729	>	9706
Total FP	57	<	89
Total FP CONTRA	11	<	17
Total FP INCONS	28	<	58
Total FP COMP	18	>	14
Total FN	70	<	83
P-value	0.0

Comparison of performance of MXScarna(seed) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and RNAwolf).
Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and RNAwolf).

Total Scores
MCC	0.593
Average MCC ± 95% Confidence Intervals	0.535 ± 0.268
Sensitivity	0.533
Positive Predictive Value	0.672
Nr of predictions	7

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	-0.03	0.00	0.00	0	518	12	0	10	2	18
3RKF_A	Purine links to Rfam database...	0.86	0.75	1.00	18	848	0	0	0	0	6
3SD1_A	THF links to Rfam database...	0.74	0.76	0.73	22	1503	9	4	4	1	7
4A1C_2	5_8S_rRNA links to Rfam database...	0.45	0.40	0.50	8	4500	20	4	4	12	12
4AOB_A	SAM links to Rfam database...	0.71	0.69	0.74	20	1410	10	2	5	3	9
4ENB_A	crcB links to Rfam database...	0.54	0.40	0.75	6	464	2	0	2	0	9
4ENC_A	crcB links to Rfam database...	0.48	0.40	0.60	6	486	4	1	3	0	9

Total Scores
MCC	0.451
Average MCC ± 95% Confidence Intervals	0.450 ± 0.230
Sensitivity	0.447
Positive Predictive Value	0.472
Nr of predictions	7

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	0.52	0.50	0.56	9	512	7	0	7	0	9
3RKF_A	Purine links to Rfam database...	0.89	0.83	0.95	20	845	1	0	1	0	4
3SD1_A	THF links to Rfam database...	0.58	0.59	0.59	17	1504	12	2	10	0	12
4A1C_2	5_8S_rRNA links to Rfam database...	0.12	0.15	0.10	3	4487	38	12	14	12	17
4AOB_A	SAM links to Rfam database...	0.26	0.24	0.30	7	1414	17	2	14	1	22
4ENB_A	crcB links to Rfam database...	0.45	0.40	0.55	6	461	5	1	4	0	9
4ENC_A	crcB links to Rfam database...	0.34	0.33	0.38	5	483	9	0	8	1	10

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.