CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MaxExpect - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MaxExpect & Multilign(20) [.zip] - may take several seconds...


Overview

Metric MaxExpect Multilign(20)
MCC 0.590 > 0.581
Average MCC ± 95% Confidence Intervals 0.601 ± 0.295 > 0.583 ± 0.267
Sensitivity 0.591 > 0.576
Positive Predictive Value 0.600 > 0.598
Total TP 78 > 76
Total TN 9190 < 9193
Total FP 68 > 60
Total FP CONTRA 17 = 17
Total FP INCONS 35 > 34
Total FP COMP 16 > 9
Total FN 54 < 56
P-value 0.0

^top




Performance plots


  1. Comparison of performance of MaxExpect and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and Multilign(20)).

^top





Performance of MaxExpect - scored higher in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 78
Total TN 9190
Total FP 68
Total FP CONTRA 17
Total FP INCONS 35
Total FP COMP 16
Total FN 54
Total Scores
MCC 0.590
Average MCC ± 95% Confidence Intervals 0.601 ± 0.295
Sensitivity 0.591
Positive Predictive Value 0.600
Nr of predictions 6

^top



2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.70 0.69 0.71 20 1505 8 3 5 0 9
4A1C_2 0.19 0.25 0.16 5 4484 41 10 17 14 15
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.36 0.33 0.42 5 484 8 0 7 1 10

^top



Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 76
Total TN 9193
Total FP 60
Total FP CONTRA 17
Total FP INCONS 34
Total FP COMP 9
Total FN 56
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.583 ± 0.267
Sensitivity 0.576
Positive Predictive Value 0.598
Nr of predictions 6

^top



2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15
4AOB_A 0.59 0.55 0.64 16 1412 10 3 6 1 13
4ENB_A 0.39 0.33 0.50 5 462 6 0 5 1 10
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.