CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric Multilign(20) RSpredict(20)
MCC 0.581 > 0.573
Average MCC ± 95% Confidence Intervals 0.583 ± 0.267 > 0.558 ± 0.276
Sensitivity 0.576 > 0.530
Positive Predictive Value 0.598 < 0.631
Total TP 76 > 70
Total TN 9193 < 9209
Total FP 60 > 48
Total FP CONTRA 17 < 19
Total FP INCONS 34 > 22
Total FP COMP 9 > 7
Total FN 56 < 62
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(20) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and RSpredict(20)).

^top





Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 76
Total TN 9193
Total FP 60
Total FP CONTRA 17
Total FP INCONS 34
Total FP COMP 9
Total FN 56
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.583 ± 0.267
Sensitivity 0.576
Positive Predictive Value 0.598
Nr of predictions 6

^top



2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15
4AOB_A 0.59 0.55 0.64 16 1412 10 3 6 1 13
4ENB_A 0.39 0.33 0.50 5 462 6 0 5 1 10
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top



Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 70
Total TN 9209
Total FP 48
Total FP CONTRA 19
Total FP INCONS 22
Total FP COMP 7
Total FN 62
Total Scores
MCC 0.573
Average MCC ± 95% Confidence Intervals 0.558 ± 0.276
Sensitivity 0.530
Positive Predictive Value 0.631
Nr of predictions 6

^top



2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 1 0 0 3
3SD1_A 0.82 0.86 0.78 25 1501 7 5 2 0 4
4A1C_2 0.25 0.30 0.21 6 4487 30 12 11 7 14
4AOB_A 0.33 0.21 0.55 6 1426 5 1 4 0 23
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.51 0.40 0.67 6 487 3 0 3 0 9

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.