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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Mastr(20)
MCC 0.755 > 0.656
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321 > 0.662 ± 0.544
Sensitivity 0.707 > 0.585
Positive Predictive Value 0.817 > 0.750
Total TP 58 > 48
Total TN 3765 < 3772
Total FP 14 < 17
Total FP CONTRA 5 = 5
Total FP INCONS 8 < 11
Total FP COMP 1 = 1
Total FN 24 < 34
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 3765
Total FP 14
Total FP CONTRA 5
Total FP INCONS 8
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.755
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321
Sensitivity 0.707
Positive Predictive Value 0.817
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 48
Total TN 3772
Total FP 17
Total FP CONTRA 5
Total FP INCONS 11
Total FP COMP 1
Total FN 34
Total Scores
MCC 0.656
Average MCC ± 95% Confidence Intervals 0.662 ± 0.544
Sensitivity 0.585
Positive Predictive Value 0.750
Nr of predictions 3

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.