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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Multilign(20)
MCC 0.755 > 0.716
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321 > 0.727 ± 0.414
Sensitivity 0.707 > 0.695
Positive Predictive Value 0.817 > 0.750
Total TP 58 > 57
Total TN 3765 > 3760
Total FP 14 < 20
Total FP CONTRA 5 < 7
Total FP INCONS 8 < 12
Total FP COMP 1 = 1
Total FN 24 < 25
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Multilign(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 3765
Total FP 14
Total FP CONTRA 5
Total FP INCONS 8
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.755
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321
Sensitivity 0.707
Positive Predictive Value 0.817
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 57
Total TN 3760
Total FP 20
Total FP CONTRA 7
Total FP INCONS 12
Total FP COMP 1
Total FN 25
Total Scores
MCC 0.716
Average MCC ± 95% Confidence Intervals 0.727 ± 0.414
Sensitivity 0.695
Positive Predictive Value 0.750
Nr of predictions 3

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4AOB_A 0.59 0.55 0.64 16 1412 10 3 6 1 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.