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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric Multilign(seed) NanoFolder
MCC 0.458 > 0.447
Average MCC ± 95% Confidence Intervals 0.352 ± 4.820 < 0.462 ± 0.940
Sensitivity 0.404 < 0.489
Positive Predictive Value 0.543 > 0.434
Total TP 19 < 23
Total TN 1930 > 1912
Total FP 17 < 31
Total FP CONTRA 3 < 5
Total FP INCONS 13 < 25
Total FP COMP 1 = 1
Total FN 28 > 24
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and NanoFolder).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 19
Total TN 1930
Total FP 17
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 1
Total FN 28
Total Scores
MCC 0.458
Average MCC ± 95% Confidence Intervals 0.352 ± 4.820
Sensitivity 0.404
Positive Predictive Value 0.543
Nr of predictions 2

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 23
Total TN 1912
Total FP 31
Total FP CONTRA 5
Total FP INCONS 25
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.447
Average MCC ± 95% Confidence Intervals 0.462 ± 0.940
Sensitivity 0.489
Positive Predictive Value 0.434
Nr of predictions 2

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.