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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & TurboFold(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) TurboFold(20)
MCC 0.755 > 0.753
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321 > 0.763 ± 0.323
Sensitivity 0.707 > 0.695
Positive Predictive Value 0.817 < 0.826
Total TP 58 > 57
Total TN 3765 < 3767
Total FP 14 > 13
Total FP CONTRA 5 > 4
Total FP INCONS 8 = 8
Total FP COMP 1 = 1
Total FN 24 < 25
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and TurboFold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and TurboFold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and TurboFold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and TurboFold(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 3765
Total FP 14
Total FP CONTRA 5
Total FP INCONS 8
Total FP COMP 1
Total FN 24
Total Scores
MCC 0.755
Average MCC ± 95% Confidence Intervals 0.767 ± 0.321
Sensitivity 0.707
Positive Predictive Value 0.817
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of TurboFold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 57
Total TN 3767
Total FP 13
Total FP CONTRA 4
Total FP INCONS 8
Total FP COMP 1
Total FN 25
Total Scores
MCC 0.753
Average MCC ± 95% Confidence Intervals 0.763 ± 0.323
Sensitivity 0.695
Positive Predictive Value 0.826
Nr of predictions 3

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.