CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	Murlet(20)		Multilign(seed)
MCC	0.833	>	0.755
Average MCC ± 95% Confidence Intervals	0.835 ± 0.074	>	0.767 ± 0.321
Sensitivity	0.756	>	0.707
Positive Predictive Value	0.925	>	0.817
Total TP	62	>	58
Total TN	3769	>	3765
Total FP	8	<	14
Total FP CONTRA	4	<	5
Total FP INCONS	1	<	8
Total FP COMP	3	>	1
Total FN	20	<	24
P-value	0.0

Comparison of performance of Murlet(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and Multilign(seed)).
Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and Multilign(seed)).

Total Scores
MCC	0.833
Average MCC ± 95% Confidence Intervals	0.835 ± 0.074
Sensitivity	0.756
Positive Predictive Value	0.925
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.81	0.67	1.00	16	850	0	0	0	0	8
3SD1_A	THF links to Rfam database...	0.82	0.83	0.83	24	1504	5	4	1	0	5
4AOB_A	SAM links to Rfam database...	0.87	0.76	1.00	22	1415	3	0	0	3	7

Total Scores
MCC	0.755
Average MCC ± 95% Confidence Intervals	0.767 ± 0.321
Sensitivity	0.707
Positive Predictive Value	0.817
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.91	0.83	1.00	20	846	0	0	0	0	4
3SD1_A	THF links to Rfam database...	0.66	0.66	0.68	19	1505	9	4	5	0	10
4AOB_A	SAM links to Rfam database...	0.73	0.66	0.83	19	1414	5	1	3	1	10

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.