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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(20) PPfold(seed)
MCC 0.654 > 0.036
Average MCC ± 95% Confidence Intervals 0.635 ± 0.263 > 0.016 ± 0.042
Sensitivity 0.576 > 0.008
Positive Predictive Value 0.752 > 0.200
Total TP 76 > 1
Total TN 9219 < 9315
Total FP 32 > 23
Total FP CONTRA 9 > 0
Total FP INCONS 16 > 4
Total FP COMP 7 < 19
Total FN 56 < 131
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and PPfold(seed)).

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Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 76
Total TN 9219
Total FP 32
Total FP CONTRA 9
Total FP INCONS 16
Total FP COMP 7
Total FN 56
Total Scores
MCC 0.654
Average MCC ± 95% Confidence Intervals 0.635 ± 0.263
Sensitivity 0.576
Positive Predictive Value 0.752
Nr of predictions 6

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.81 0.67 1.00 16 850 0 0 0 0 8
3SD1_A 0.82 0.83 0.83 24 1504 5 4 1 0 5
4A1C_2 0.22 0.25 0.20 5 4491 24 5 15 4 15
4AOB_A 0.87 0.76 1.00 22 1415 3 0 0 3 7
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 1
Total TN 9315
Total FP 23
Total FP CONTRA 0
Total FP INCONS 4
Total FP COMP 19
Total FN 131
Total Scores
MCC 0.036
Average MCC ± 95% Confidence Intervals 0.016 ± 0.042
Sensitivity 0.008
Positive Predictive Value 0.200
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.10 0.05 0.20 1 4511 23 0 4 19 19
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.