CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & RNASLOpt [.zip] - may take several seconds...


Overview

Metric NanoFolder RNASLOpt
MCC 0.427 > 0.420
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376 > 0.464 ± 0.215
Sensitivity 0.519 > 0.423
Positive Predictive Value 0.365 < 0.431
Total TP 54 > 44
Total TN 8105 < 8151
Total FP 113 > 67
Total FP CONTRA 31 > 20
Total FP INCONS 63 > 38
Total FP COMP 19 > 9
Total FN 50 < 60
P-value 0.0

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Performance plots


  1. Comparison of performance of NanoFolder and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and RNASLOpt).

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Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 54
Total TN 8105
Total FP 113
Total FP CONTRA 31
Total FP INCONS 63
Total FP COMP 19
Total FN 50
Total Scores
MCC 0.427
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376
Sensitivity 0.519
Positive Predictive Value 0.365
Nr of predictions 5

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3U4M_B - 0.77 0.91 0.67 20 1246 12 6 4 2 2
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 44
Total TN 8151
Total FP 67
Total FP CONTRA 20
Total FP INCONS 38
Total FP COMP 9
Total FN 60
Total Scores
MCC 0.420
Average MCC ± 95% Confidence Intervals 0.464 ± 0.215
Sensitivity 0.423
Positive Predictive Value 0.431
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.