CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of RNAsubopt - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & RNAsubopt [.zip] - may take several seconds...


Overview

Metric NanoFolder RNAsubopt
MCC 0.427 > 0.356
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376 > 0.325 ± 0.320
Sensitivity 0.519 > 0.385
Positive Predictive Value 0.365 > 0.345
Total TP 54 > 40
Total TN 8105 < 8137
Total FP 113 > 90
Total FP CONTRA 31 > 23
Total FP INCONS 63 > 53
Total FP COMP 19 > 14
Total FN 50 < 64
P-value 0.0

^top




Performance plots


  1. Comparison of performance of NanoFolder and RNAsubopt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and RNAsubopt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and RNAsubopt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and RNAsubopt).

^top





Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 54
Total TN 8105
Total FP 113
Total FP CONTRA 31
Total FP INCONS 63
Total FP COMP 19
Total FN 50
Total Scores
MCC 0.427
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376
Sensitivity 0.519
Positive Predictive Value 0.365
Nr of predictions 5

^top



2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3U4M_B - 0.77 0.91 0.67 20 1246 12 6 4 2 2
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

^top



Performance of RNAsubopt - scored lower in this pairwise comparison

1. Total counts & total scores for RNAsubopt

Total Base Pair Counts
Total TP 40
Total TN 8137
Total FP 90
Total FP CONTRA 23
Total FP INCONS 53
Total FP COMP 14
Total FN 64
Total Scores
MCC 0.356
Average MCC ± 95% Confidence Intervals 0.325 ± 0.320
Sensitivity 0.385
Positive Predictive Value 0.345
Nr of predictions 5

^top



2. Individual counts for RNAsubopt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2 0.18 0.25 0.14 5 4481 43 13 17 13 15
4AOB_A 0.62 0.62 0.64 18 1409 11 4 6 1 11
4ENC_A 0.36 0.33 0.42 5 484 7 0 7 0 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.