CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & RNAwolf [.zip] - may take several seconds...


Overview

Metric NanoFolder RNAwolf
MCC 0.427 > 0.332
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376 > 0.347 ± 0.208
Sensitivity 0.519 > 0.337
Positive Predictive Value 0.365 > 0.343
Total TP 54 > 35
Total TN 8105 < 8151
Total FP 113 > 83
Total FP CONTRA 31 > 15
Total FP INCONS 63 > 52
Total FP COMP 19 > 16
Total FN 50 < 69
P-value 0.0

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Performance plots


  1. Comparison of performance of NanoFolder and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and RNAwolf).

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Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 54
Total TN 8105
Total FP 113
Total FP CONTRA 31
Total FP INCONS 63
Total FP COMP 19
Total FN 50
Total Scores
MCC 0.427
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376
Sensitivity 0.519
Positive Predictive Value 0.365
Nr of predictions 5

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3U4M_B - 0.77 0.91 0.67 20 1246 12 6 4 2 2
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 35
Total TN 8151
Total FP 83
Total FP CONTRA 15
Total FP INCONS 52
Total FP COMP 16
Total FN 69
Total Scores
MCC 0.332
Average MCC ± 95% Confidence Intervals 0.347 ± 0.208
Sensitivity 0.337
Positive Predictive Value 0.343
Nr of predictions 5

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.50 0.56 9 512 7 0 7 0 9
3U4M_B - 0.50 0.50 0.52 11 1255 12 1 9 2 11
4A1C_2 0.12 0.15 0.10 3 4487 38 12 14 12 17
4AOB_A 0.26 0.24 0.30 7 1414 17 2 14 1 22
4ENC_A 0.34 0.33 0.38 5 483 9 0 8 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.