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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of CentroidFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & CentroidFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) CentroidFold
MCC 0.619 > 0.531
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416 < 0.605 ± 0.491
Sensitivity 0.570 > 0.519
Positive Predictive Value 0.682 > 0.554
Total TP 45 > 41
Total TN 6855 > 6847
Total FP 33 < 44
Total FP CONTRA 2 < 12
Total FP INCONS 19 < 21
Total FP COMP 12 > 11
Total FN 34 < 38
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and CentroidFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and CentroidFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidFold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 45
Total TN 6855
Total FP 33
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 12
Total FN 34
Total Scores
MCC 0.619
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416
Sensitivity 0.570
Positive Predictive Value 0.682
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of CentroidFold - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidFold

Total Base Pair Counts
Total TP 41
Total TN 6847
Total FP 44
Total FP CONTRA 12
Total FP INCONS 21
Total FP COMP 11
Total FN 38
Total Scores
MCC 0.531
Average MCC ± 95% Confidence Intervals 0.605 ± 0.491
Sensitivity 0.519
Positive Predictive Value 0.554
Nr of predictions 4

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2. Individual counts for CentroidFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.19 5 4490 29 9 12 8 15
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15
4ENB_A 0.85 0.73 1.00 11 461 1 0 0 1 4
4ENC_A 0.85 0.73 1.00 11 485 1 0 0 1 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.