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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Cylofold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Cylofold
MCC 0.763 > 0.720
Average MCC ± 95% Confidence Intervals 0.722 ± 0.333 < 0.794 ± 0.816
Sensitivity 0.678 < 0.695
Positive Predictive Value 0.870 > 0.759
Total TP 40 < 41
Total TN 2359 > 2351
Total FP 8 < 14
Total FP CONTRA 0 < 4
Total FP INCONS 6 < 9
Total FP COMP 2 > 1
Total FN 19 > 18
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Cylofold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 40
Total TN 2359
Total FP 8
Total FP CONTRA 0
Total FP INCONS 6
Total FP COMP 2
Total FN 19
Total Scores
MCC 0.763
Average MCC ± 95% Confidence Intervals 0.722 ± 0.333
Sensitivity 0.678
Positive Predictive Value 0.870
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 41
Total TN 2351
Total FP 14
Total FP CONTRA 4
Total FP INCONS 9
Total FP COMP 1
Total FN 18
Total Scores
MCC 0.720
Average MCC ± 95% Confidence Intervals 0.794 ± 0.816
Sensitivity 0.695
Positive Predictive Value 0.759
Nr of predictions 3

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.