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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & NanoFolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) NanoFolder
MCC 0.609 > 0.285
Average MCC ± 95% Confidence Intervals 0.577 ± 0.780 > 0.346 ± 0.831
Sensitivity 0.578 > 0.359
Positive Predictive Value 0.649 > 0.240
Total TP 37 > 23
Total TN 6392 > 6353
Total FP 32 < 90
Total FP CONTRA 2 < 24
Total FP INCONS 18 < 49
Total FP COMP 12 < 17
Total FN 27 < 41
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 37
Total TN 6392
Total FP 32
Total FP CONTRA 2
Total FP INCONS 18
Total FP COMP 12
Total FN 27
Total Scores
MCC 0.609
Average MCC ± 95% Confidence Intervals 0.577 ± 0.780
Sensitivity 0.578
Positive Predictive Value 0.649
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 23
Total TN 6353
Total FP 90
Total FP CONTRA 24
Total FP INCONS 49
Total FP COMP 17
Total FN 41
Total Scores
MCC 0.285
Average MCC ± 95% Confidence Intervals 0.346 ± 0.831
Sensitivity 0.359
Positive Predictive Value 0.240
Nr of predictions 3

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.