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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RNAsubopt - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RNAsubopt [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RNAsubopt
MCC 0.619 > 0.467
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416 > 0.504 ± 0.469
Sensitivity 0.570 > 0.494
Positive Predictive Value 0.682 > 0.453
Total TP 45 > 39
Total TN 6855 > 6835
Total FP 33 < 63
Total FP CONTRA 2 < 17
Total FP INCONS 19 < 30
Total FP COMP 12 < 16
Total FN 34 < 40
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RNAsubopt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAsubopt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RNAsubopt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAsubopt).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 45
Total TN 6855
Total FP 33
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 12
Total FN 34
Total Scores
MCC 0.619
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416
Sensitivity 0.570
Positive Predictive Value 0.682
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of RNAsubopt - scored lower in this pairwise comparison

1. Total counts & total scores for RNAsubopt

Total Base Pair Counts
Total TP 39
Total TN 6835
Total FP 63
Total FP CONTRA 17
Total FP INCONS 30
Total FP COMP 16
Total FN 40
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.504 ± 0.469
Sensitivity 0.494
Positive Predictive Value 0.453
Nr of predictions 4

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2. Individual counts for RNAsubopt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.18 0.25 0.14 5 4481 43 13 17 13 15
4AOB_A 0.62 0.62 0.64 18 1409 11 4 6 1 11
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.36 0.33 0.42 5 484 7 0 7 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.