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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Vsfold5
MCC 0.619 > 0.535
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416 < 0.627 ± 0.659
Sensitivity 0.570 > 0.557
Positive Predictive Value 0.682 > 0.524
Total TP 45 > 44
Total TN 6855 > 6837
Total FP 33 < 57
Total FP CONTRA 2 < 11
Total FP INCONS 19 < 29
Total FP COMP 12 < 17
Total FN 34 < 35
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Vsfold5. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Vsfold5).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Vsfold5. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Vsfold5).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 45
Total TN 6855
Total FP 33
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 12
Total FN 34
Total Scores
MCC 0.619
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416
Sensitivity 0.570
Positive Predictive Value 0.682
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 44
Total TN 6837
Total FP 57
Total FP CONTRA 11
Total FP INCONS 29
Total FP COMP 17
Total FN 35
Total Scores
MCC 0.535
Average MCC ± 95% Confidence Intervals 0.627 ± 0.659
Sensitivity 0.557
Positive Predictive Value 0.524
Nr of predictions 4

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2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.33 0.40 0.28 8 4487 37 8 13 16 12
4AOB_A 0.21 0.21 0.25 6 1413 19 2 16 1 23
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.