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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of ContextFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & ContextFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) ContextFold
MCC 0.695 > 0.570
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215 > 0.592 ± 0.249
Sensitivity 0.619 > 0.515
Positive Predictive Value 0.789 > 0.641
Total TP 60 > 50
Total TN 7373 > 7371
Total FP 31 < 42
Total FP CONTRA 3 < 6
Total FP INCONS 13 < 22
Total FP COMP 15 > 14
Total FN 37 < 47
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and ContextFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and ContextFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and ContextFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and ContextFold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 60
Total TN 7373
Total FP 31
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 15
Total FN 37
Total Scores
MCC 0.695
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215
Sensitivity 0.619
Positive Predictive Value 0.789
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of ContextFold - scored lower in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 50
Total TN 7371
Total FP 42
Total FP CONTRA 6
Total FP INCONS 22
Total FP COMP 14
Total FN 47
Total Scores
MCC 0.570
Average MCC ± 95% Confidence Intervals 0.592 ± 0.249
Sensitivity 0.515
Positive Predictive Value 0.641
Nr of predictions 5

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.