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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of MCFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & MCFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) MCFold
MCC 0.625 > 0.388
Average MCC ± 95% Confidence Intervals 0.607 ± 0.246 > 0.435 ± 0.404
Sensitivity 0.544 > 0.426
Positive Predictive Value 0.725 > 0.367
Total TP 37 > 29
Total TN 5961 > 5933
Total FP 27 < 70
Total FP CONTRA 3 < 12
Total FP INCONS 11 < 38
Total FP COMP 13 < 20
Total FN 31 < 39
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and MCFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and MCFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 37
Total TN 5961
Total FP 27
Total FP CONTRA 3
Total FP INCONS 11
Total FP COMP 13
Total FN 31
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.607 ± 0.246
Sensitivity 0.544
Positive Predictive Value 0.725
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of MCFold - scored lower in this pairwise comparison

1. Total counts & total scores for MCFold

Total Base Pair Counts
Total TP 29
Total TN 5933
Total FP 70
Total FP CONTRA 12
Total FP INCONS 38
Total FP COMP 20
Total FN 39
Total Scores
MCC 0.388
Average MCC ± 95% Confidence Intervals 0.435 ± 0.404
Sensitivity 0.426
Positive Predictive Value 0.367
Nr of predictions 4

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2. Individual counts for MCFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.44 0.44 0.47 8 511 10 0 9 1 10
4A1C_2 0.18 0.25 0.14 5 4480 45 12 19 14 15
4ENB_A 0.78 0.73 0.85 11 459 4 0 2 2 4
4ENC_A 0.34 0.33 0.38 5 483 11 0 8 3 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.