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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) MXScarna(20)
MCC 0.751 > 0.477
Average MCC ± 95% Confidence Intervals 0.717 ± 0.195 > 0.469 ± 0.391
Sensitivity 0.684 > 0.430
Positive Predictive Value 0.831 > 0.540
Total TP 54 > 34
Total TN 6856 < 6858
Total FP 26 < 50
Total FP CONTRA 3 < 10
Total FP INCONS 8 < 19
Total FP COMP 15 < 21
Total FN 25 < 45
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MXScarna(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MXScarna(20)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 54
Total TN 6856
Total FP 26
Total FP CONTRA 3
Total FP INCONS 8
Total FP COMP 15
Total FN 25
Total Scores
MCC 0.751
Average MCC ± 95% Confidence Intervals 0.717 ± 0.195
Sensitivity 0.684
Positive Predictive Value 0.831
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 34
Total TN 6858
Total FP 50
Total FP CONTRA 10
Total FP INCONS 19
Total FP COMP 21
Total FN 45
Total Scores
MCC 0.477
Average MCC ± 95% Confidence Intervals 0.469 ± 0.391
Sensitivity 0.430
Positive Predictive Value 0.540
Nr of predictions 4

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.