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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of McQFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & McQFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) McQFold
MCC 0.695 > 0.589
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215 < 0.660 ± 0.418
Sensitivity 0.619 = 0.619
Positive Predictive Value 0.789 > 0.571
Total TP 60 = 60
Total TN 7373 > 7344
Total FP 31 < 52
Total FP CONTRA 3 < 16
Total FP INCONS 13 < 29
Total FP COMP 15 > 7
Total FN 37 = 37
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and McQFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and McQFold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 60
Total TN 7373
Total FP 31
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 15
Total FN 37
Total Scores
MCC 0.695
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215
Sensitivity 0.619
Positive Predictive Value 0.789
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of McQFold - scored lower in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 60
Total TN 7344
Total FP 52
Total FP CONTRA 16
Total FP INCONS 29
Total FP COMP 7
Total FN 37
Total Scores
MCC 0.589
Average MCC ± 95% Confidence Intervals 0.660 ± 0.418
Sensitivity 0.619
Positive Predictive Value 0.571
Nr of predictions 5

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
4A1C_2 0.19 0.25 0.16 5 4484 33 11 16 6 15
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.