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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Multilign(seed)
MCC 0.699 > 0.458
Average MCC ± 95% Confidence Intervals 0.631 ± 2.796 > 0.352 ± 4.820
Sensitivity 0.617 > 0.404
Positive Predictive Value 0.806 > 0.543
Total TP 29 > 19
Total TN 1929 < 1930
Total FP 9 < 17
Total FP CONTRA 0 < 3
Total FP INCONS 7 < 13
Total FP COMP 2 > 1
Total FN 18 < 28
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Multilign(seed)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 29
Total TN 1929
Total FP 9
Total FP CONTRA 0
Total FP INCONS 7
Total FP COMP 2
Total FN 18
Total Scores
MCC 0.699
Average MCC ± 95% Confidence Intervals 0.631 ± 2.796
Sensitivity 0.617
Positive Predictive Value 0.806
Nr of predictions 2

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 19
Total TN 1930
Total FP 17
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 1
Total FN 28
Total Scores
MCC 0.458
Average MCC ± 95% Confidence Intervals 0.352 ± 4.820
Sensitivity 0.404
Positive Predictive Value 0.543
Nr of predictions 2

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.