CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) RSpredict(seed)
MCC 0.695 > 0.203
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215 > 0.211 ± 0.261
Sensitivity 0.619 > 0.124
Positive Predictive Value 0.789 > 0.353
Total TP 60 > 12
Total TN 7373 < 7415
Total FP 31 > 23
Total FP CONTRA 3 > 2
Total FP INCONS 13 < 20
Total FP COMP 15 > 1
Total FN 37 < 85
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RSpredict(seed)).

^top





Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 60
Total TN 7373
Total FP 31
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 15
Total FN 37
Total Scores
MCC 0.695
Average MCC ± 95% Confidence Intervals 0.656 ± 0.215
Sensitivity 0.619
Positive Predictive Value 0.789
Nr of predictions 5

^top



2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

^top



Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 12
Total TN 7415
Total FP 23
Total FP CONTRA 2
Total FP INCONS 20
Total FP COMP 1
Total FN 85
Total Scores
MCC 0.203
Average MCC ± 95% Confidence Intervals 0.211 ± 0.261
Sensitivity 0.124
Positive Predictive Value 0.353
Nr of predictions 5

^top



2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 515 13 0 13 0 18
4A1C_2 0.00 0.00 0.00 0 4512 5 2 2 1 20
4AOB_A 0.42 0.21 0.86 6 1430 1 0 1 0 23
4ENB_A 0.34 0.20 0.60 3 467 2 0 2 0 12
4ENC_A 0.34 0.20 0.60 3 491 2 0 2 0 12

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.