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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of PETfold_pre2.0(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & PETfold_pre2.0(20) [.zip] - may take several seconds...


Overview

Metric PPfold(20) PETfold_pre2.0(20)
MCC 0.630 > 0.619
Average MCC ± 95% Confidence Intervals 0.604 ± 0.397 > 0.603 ± 0.416
Sensitivity 0.557 < 0.570
Positive Predictive Value 0.721 > 0.682
Total TP 44 < 45
Total TN 6860 > 6855
Total FP 23 < 33
Total FP CONTRA 1 < 2
Total FP INCONS 16 < 19
Total FP COMP 6 < 12
Total FN 35 > 34
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and PETfold_pre2.0(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and PETfold_pre2.0(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and PETfold_pre2.0(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and PETfold_pre2.0(20)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 44
Total TN 6860
Total FP 23
Total FP CONTRA 1
Total FP INCONS 16
Total FP COMP 6
Total FN 35
Total Scores
MCC 0.630
Average MCC ± 95% Confidence Intervals 0.604 ± 0.397
Sensitivity 0.557
Positive Predictive Value 0.721
Nr of predictions 4

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

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Performance of PETfold_pre2.0(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 45
Total TN 6855
Total FP 33
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 12
Total FN 34
Total Scores
MCC 0.619
Average MCC ± 95% Confidence Intervals 0.603 ± 0.416
Sensitivity 0.570
Positive Predictive Value 0.682
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.