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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric PPfold(20) RNASampler(seed)
MCC 0.681 > 0.679
Average MCC ± 95% Confidence Intervals 0.649 ± 0.821 < 0.675 ± 0.644
Sensitivity 0.630 > 0.603
Positive Predictive Value 0.742 < 0.772
Total TP 46 > 44
Total TN 6853 < 6858
Total FP 20 < 21
Total FP CONTRA 3 < 4
Total FP INCONS 13 > 9
Total FP COMP 4 < 8
Total FN 27 < 29
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and RNASampler(seed)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 46
Total TN 6853
Total FP 20
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 4
Total FN 27
Total Scores
MCC 0.681
Average MCC ± 95% Confidence Intervals 0.649 ± 0.821
Sensitivity 0.630
Positive Predictive Value 0.742
Nr of predictions 3

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 6858
Total FP 21
Total FP CONTRA 4
Total FP INCONS 9
Total FP COMP 8
Total FN 29
Total Scores
MCC 0.679
Average MCC ± 95% Confidence Intervals 0.675 ± 0.644
Sensitivity 0.603
Positive Predictive Value 0.772
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.