CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric PPfold(20) RSpredict(seed)
MCC 0.715 > 0.409
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240 > 0.321 ± 0.327
Sensitivity 0.644 > 0.227
Positive Predictive Value 0.802 > 0.750
Total TP 85 > 30
Total TN 9214 < 9280
Total FP 27 > 11
Total FP CONTRA 3 = 3
Total FP INCONS 18 > 7
Total FP COMP 6 > 1
Total FN 47 < 102
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PPfold(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and RSpredict(seed)).

^top





Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 85
Total TN 9214
Total FP 27
Total FP CONTRA 3
Total FP INCONS 18
Total FP COMP 6
Total FN 47
Total Scores
MCC 0.715
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240
Sensitivity 0.644
Positive Predictive Value 0.802
Nr of predictions 6

^top



2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

^top



Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 30
Total TN 9280
Total FP 11
Total FP CONTRA 3
Total FP INCONS 7
Total FP COMP 1
Total FN 102
Total Scores
MCC 0.409
Average MCC ± 95% Confidence Intervals 0.321 ± 0.327
Sensitivity 0.227
Positive Predictive Value 0.750
Nr of predictions 6

^top



2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.84 0.75 0.95 18 847 1 1 0 0 6
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4512 5 2 2 1 20
4AOB_A 0.42 0.21 0.86 6 1430 1 0 1 0 23
4ENB_A 0.34 0.20 0.60 3 467 2 0 2 0 12
4ENC_A 0.34 0.20 0.60 3 491 2 0 2 0 12

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.