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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Sfold - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Sfold [.zip] - may take several seconds...


Overview

Metric PPfold(20) Sfold
MCC 0.715 > 0.636
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240 > 0.654 ± 0.268
Sensitivity 0.644 > 0.598
Positive Predictive Value 0.802 > 0.687
Total TP 85 > 79
Total TN 9214 > 9205
Total FP 27 < 49
Total FP CONTRA 3 < 14
Total FP INCONS 18 < 22
Total FP COMP 6 < 13
Total FN 47 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and Sfold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Sfold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Sfold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Sfold).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 85
Total TN 9214
Total FP 27
Total FP CONTRA 3
Total FP INCONS 18
Total FP COMP 6
Total FN 47
Total Scores
MCC 0.715
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240
Sensitivity 0.644
Positive Predictive Value 0.802
Nr of predictions 6

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

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Performance of Sfold - scored lower in this pairwise comparison

1. Total counts & total scores for Sfold

Total Base Pair Counts
Total TP 79
Total TN 9205
Total FP 49
Total FP CONTRA 14
Total FP INCONS 22
Total FP COMP 13
Total FN 53
Total Scores
MCC 0.636
Average MCC ± 95% Confidence Intervals 0.654 ± 0.268
Sensitivity 0.598
Positive Predictive Value 0.687
Nr of predictions 6

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2. Individual counts for Sfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.78 0.72 0.84 21 1508 4 2 2 0 8
4A1C_2 0.21 0.25 0.19 5 4489 34 8 14 12 15
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.