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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric PPfold(20) Vsfold4
MCC 0.715 > 0.544
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240 > 0.604 ± 0.295
Sensitivity 0.644 > 0.523
Positive Predictive Value 0.802 > 0.580
Total TP 85 > 69
Total TN 9214 > 9201
Total FP 27 < 63
Total FP CONTRA 3 < 12
Total FP INCONS 18 < 38
Total FP COMP 6 < 13
Total FN 47 < 63
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Vsfold4).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Vsfold4).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 85
Total TN 9214
Total FP 27
Total FP CONTRA 3
Total FP INCONS 18
Total FP COMP 6
Total FN 47
Total Scores
MCC 0.715
Average MCC ± 95% Confidence Intervals 0.682 ± 0.240
Sensitivity 0.644
Positive Predictive Value 0.802
Nr of predictions 6

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 69
Total TN 9201
Total FP 63
Total FP CONTRA 12
Total FP INCONS 38
Total FP COMP 13
Total FN 63
Total Scores
MCC 0.544
Average MCC ± 95% Confidence Intervals 0.604 ± 0.295
Sensitivity 0.523
Positive Predictive Value 0.580
Nr of predictions 6

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.23 0.24 0.24 7 1504 22 5 17 0 22
4A1C_2 0.36 0.40 0.33 8 4492 28 4 12 12 12
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.77 0.60 1.00 9 487 0 0 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.