CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PknotsRG - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PknotsRG & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric PknotsRG Mastr(seed)
MCC 0.634 > 0.000
Average MCC ± 95% Confidence Intervals 0.687 ± 0.148 > 0.000 ± 0.000
Sensitivity 0.675 > 0.000
Positive Predictive Value 0.602 > 0.000
Total TP 388 > 0
Total TN 77070 < 77715
Total FP 306 > 0
Total FP CONTRA 111 > 0
Total FP INCONS 146 > 0
Total FP COMP 49 > 0
Total FN 187 < 575
P-value 2.97012568641e-08

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Performance plots


  1. Comparison of performance of PknotsRG and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PknotsRG and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PknotsRG and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PknotsRG and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PknotsRG and Mastr(seed)).

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Performance of PknotsRG - scored higher in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 388
Total TN 77070
Total FP 306
Total FP CONTRA 111
Total FP INCONS 146
Total FP COMP 49
Total FN 187
Total Scores
MCC 0.634
Average MCC ± 95% Confidence Intervals 0.687 ± 0.148
Sensitivity 0.675
Positive Predictive Value 0.602
Nr of predictions 19

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.66 0.61 0.73 11 513 4 2 2 0 7
2ZZN_D 0.93 0.95 0.91 21 961 2 2 0 0 1
3A2K_C 0.47 0.50 0.46 11 1084 13 3 10 0 11
3A3A_A 0.97 0.93 1.00 28 1472 0 0 0 0 2
3GX2_A 0.80 0.79 0.81 22 1422 6 2 3 1 6
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3IYQ_A 0.24 0.33 0.17 17 22340 94 45 38 11 34
3IZ4_A 0.56 0.60 0.52 57 25426 57 25 28 4 38
3JYV_7 -0.02 0.00 0.00 0 1089 22 4 18 0 20
3LA5_A 0.91 0.84 1.00 21 933 0 0 0 0 4
3NPB_A 0.93 0.86 1.00 32 2246 4 0 0 4 5
3O58_3 0.41 0.50 0.34 11 4732 35 6 15 14 11
3PDR_A 0.90 0.90 0.90 45 4790 7 2 3 2 5
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
4A1C_2 0.18 0.25 0.14 5 4480 43 11 20 12 15
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 77715
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 575
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 19

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 528 0 0 0 0 18
2ZZN_D 0.00 0.00 0.00 0 984 0 0 0 0 22
3A2K_C 0.00 0.00 0.00 0 1108 0 0 0 0 22
3A3A_A 0.00 0.00 0.00 0 1500 0 0 0 0 30
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3IYQ_A 0.00 0.00 0.00 0 22440 0 0 0 0 51
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3JYV_7 0.00 0.00 0.00 0 1111 0 0 0 0 20
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.