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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RDfolder - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RDfolder & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric RDfolder PPfold(seed)
MCC 0.451 > 0.182
Average MCC ± 95% Confidence Intervals 0.434 ± 0.316 > 0.082 ± 0.210
Sensitivity 0.385 > 0.046
Positive Predictive Value 0.556 < 0.750
Total TP 50 > 6
Total TN 5242 < 5324
Total FP 41 > 2
Total FP CONTRA 7 > 0
Total FP INCONS 33 > 2
Total FP COMP 1 > 0
Total FN 80 < 124
P-value 0.0

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Performance plots


  1. Comparison of performance of RDfolder and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RDfolder and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RDfolder and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RDfolder and PPfold(seed)).

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Performance of RDfolder - scored higher in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 50
Total TN 5242
Total FP 41
Total FP CONTRA 7
Total FP INCONS 33
Total FP COMP 1
Total FN 80
Total Scores
MCC 0.451
Average MCC ± 95% Confidence Intervals 0.434 ± 0.316
Sensitivity 0.385
Positive Predictive Value 0.556
Nr of predictions 6

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 514 14 3 11 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.35 0.24 0.54 7 1520 6 1 5 0 22
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 0.48 0.40 0.60 6 462 4 0 4 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 0 4 0 9

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 6
Total TN 5324
Total FP 2
Total FP CONTRA 0
Total FP INCONS 2
Total FP COMP 0
Total FN 124
Total Scores
MCC 0.182
Average MCC ± 95% Confidence Intervals 0.082 ± 0.210
Sensitivity 0.046
Positive Predictive Value 0.750
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.49 0.33 0.75 6 520 2 0 2 0 12
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.