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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Afold [.zip] - may take several seconds...


Overview

Metric RNASLOpt Afold
MCC 0.479 > 0.477
Average MCC ± 95% Confidence Intervals 0.533 ± 0.367 < 0.533 ± 0.420
Sensitivity 0.507 < 0.520
Positive Predictive Value 0.463 > 0.448
Total TP 38 < 39
Total TN 6710 > 6705
Total FP 53 < 66
Total FP CONTRA 16 > 14
Total FP INCONS 28 < 34
Total FP COMP 9 < 18
Total FN 37 > 36
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Afold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Afold).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 38
Total TN 6710
Total FP 53
Total FP CONTRA 16
Total FP INCONS 28
Total FP COMP 9
Total FN 37
Total Scores
MCC 0.479
Average MCC ± 95% Confidence Intervals 0.533 ± 0.367
Sensitivity 0.507
Positive Predictive Value 0.463
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A

GP_knot1 links to Rfam database...

0.48 0.39 0.64 7 517 4 0 4 0 11
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2

5_8S_rRNA links to Rfam database...

0.30 0.40 0.24 8 4482 35 13 13 9 12
4ENB_A

crcB links to Rfam database...

0.85 0.73 1.00 11 461 0 0 0 0 4

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 39
Total TN 6705
Total FP 66
Total FP CONTRA 14
Total FP INCONS 34
Total FP COMP 18
Total FN 36
Total Scores
MCC 0.477
Average MCC ± 95% Confidence Intervals 0.533 ± 0.420
Sensitivity 0.520
Positive Predictive Value 0.448
Nr of predictions 4

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A

GP_knot1 links to Rfam database...

0.64 0.61 0.69 11 512 6 0 5 1 7
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2

5_8S_rRNA links to Rfam database...

0.19 0.25 0.15 5 4483 43 11 17 15 15
4ENB_A

crcB links to Rfam database...

0.81 0.73 0.92 11 460 3 0 1 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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