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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt PPfold(seed)
MCC 0.461 > 0.194
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307 > 0.118 ± 0.264
Sensitivity 0.443 > 0.072
Positive Predictive Value 0.494 < 0.538
Total TP 43 > 7
Total TN 7362 < 7436
Total FP 53 > 25
Total FP CONTRA 17 > 0
Total FP INCONS 27 > 6
Total FP COMP 9 < 19
Total FN 54 < 90
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and PPfold(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 7362
Total FP 53
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 9
Total FN 54
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307
Sensitivity 0.443
Positive Predictive Value 0.494
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 7
Total TN 7436
Total FP 25
Total FP CONTRA 0
Total FP INCONS 6
Total FP COMP 19
Total FN 90
Total Scores
MCC 0.194
Average MCC ± 95% Confidence Intervals 0.118 ± 0.264
Sensitivity 0.072
Positive Predictive Value 0.538
Nr of predictions 5

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.49 0.33 0.75 6 520 2 0 2 0 12
4A1C_2 0.10 0.05 0.20 1 4511 23 0 4 19 19
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.