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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt RSpredict(seed)
MCC 0.461 > 0.203
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307 > 0.211 ± 0.261
Sensitivity 0.443 > 0.124
Positive Predictive Value 0.494 > 0.353
Total TP 43 > 12
Total TN 7362 < 7415
Total FP 53 > 23
Total FP CONTRA 17 > 2
Total FP INCONS 27 > 20
Total FP COMP 9 > 1
Total FN 54 < 85
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RSpredict(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 7362
Total FP 53
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 9
Total FN 54
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307
Sensitivity 0.443
Positive Predictive Value 0.494
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 12
Total TN 7415
Total FP 23
Total FP CONTRA 2
Total FP INCONS 20
Total FP COMP 1
Total FN 85
Total Scores
MCC 0.203
Average MCC ± 95% Confidence Intervals 0.211 ± 0.261
Sensitivity 0.124
Positive Predictive Value 0.353
Nr of predictions 5

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 515 13 0 13 0 18
4A1C_2 0.00 0.00 0.00 0 4512 5 2 2 1 20
4AOB_A 0.42 0.21 0.86 6 1430 1 0 1 0 23
4ENB_A 0.34 0.20 0.60 3 467 2 0 2 0 12
4ENC_A 0.34 0.20 0.60 3 491 2 0 2 0 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.