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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt TurboFold(seed)
MCC 0.461 > 0.431
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307 > 0.467 ± 0.448
Sensitivity 0.443 > 0.412
Positive Predictive Value 0.494 > 0.465
Total TP 43 > 40
Total TN 7362 < 7363
Total FP 53 < 59
Total FP CONTRA 17 > 15
Total FP INCONS 27 < 31
Total FP COMP 9 < 13
Total FN 54 < 57
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and TurboFold(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 7362
Total FP 53
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 9
Total FN 54
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307
Sensitivity 0.443
Positive Predictive Value 0.494
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 40
Total TN 7363
Total FP 59
Total FP CONTRA 15
Total FP INCONS 31
Total FP COMP 13
Total FN 57
Total Scores
MCC 0.431
Average MCC ± 95% Confidence Intervals 0.467 ± 0.448
Sensitivity 0.412
Positive Predictive Value 0.465
Nr of predictions 5

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.